Mereo BioPharma (MREO) long speculation

65
Mereo BioPharma (MREO) is a biotechnology company with a very small market capitalization – currently below 500 million USD. The company has no revenues and is fully dependent on a single key project: a clinical trial for a treatment of osteogenesis imperfecta (commonly known as brittle bone disease).

It is currently in Phase III of the clinical trial (ORBIT), with final results expected by the end of 2025. The project is partnered with U.S.-based Ultragenyx, which is responsible for the commercialization of the therapy. According to recent data, the company has sufficient cash to operate at least through 2027.

MREO stock plunged more than 30% in a single day after the company announced it is entering the final analysis phase of the study – a move the market interpreted as a risk signal. The significant price gap downward highlights how sensitive the stock is to uncertainty in clinical development.

Despite this, analysts still see substantial long-term upside. JPMorgan has a price target of $7 (Overweight), BTIG sees $6 (Buy), and Needham recently lowered its target from $7 to $5 (Buy). The average target is around $7.50, suggesting a potential upside of +100% to +230% from the current price near $2.90.

That said, this is a highly speculative investment. The company’s tiny market cap brings high volatility. With only one promising molecule in its pipeline, any failure in clinical results could lead to a significant drop in valuation. But if successful, the stock could rise dramatically.

Disclaimer: This content is provided for informational and educational purposes only. It does not constitute investment advice or a recommendation to buy or sell securities. Investing in biotechnology companies carries high risk and may result in partial or total capital loss. Always make investment decisions independently or consult with a licensed financial advisor.

Disclaimer

The information and publications are not meant to be, and do not constitute, financial, investment, trading, or other types of advice or recommendations supplied or endorsed by TradingView. Read more in the Terms of Use.